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- Shandilya MC V, Addo-Osafo K, Ranasinghe KG, Shamas M, Staba R, Nagaragan SS, Vossel K. High frequency oscillations in epileptic and non-epileptic Alzheimer’s disease patients and the differential effect of levetiracetam on the oscillations. Brain Communications 2025, 7:fcaf041. doi: 10.1093/braincomms/fcaf041. PMC11822293
- Leuchter MK, Oughli HA, Durbin KA, Jackson NJ, Elashoff D, Chang TS, Corlier JC, Ngo D, Matthews C, Wong D, Fogel BL, Bitan G, Leuchter AF, Vossel K, Suthana N. Broad Repetitive Transcranial Magnetic Stimulation (rTMS) of the Precuneus in Alzheimer’s Disease: A Rationale and Study Design. Alzheimer's & Dementia: Translational Research & Clinical Interventions 2025, 11:e70043. doi: 10.1002/trc2.70043. PMC11891574
- Kim H, Lee J, Qian A, Ji Y-R, Zhang R, Hu Q, Williams CK, Zhang T, Vinters HV, Posadas EM, Tan ZS, Vossel K, Magaki S, Zhu Y, and Tseng H-R. Noninvasive Assessment of β-secretase Activity Through Click Chemistry-Mediated Enrichment of Neuronal Extracellular Vesicles to Detect Alzheimer’s Disease. Advanced Science 2025. In Press.
- Babiloni C, Arakaki X, Baez S, Barry RJ, Benussi A, Blinowska K, Bonanni L, Borroni B, Bayard JB, Bruno G, Cacciotti A, Carducci F, Carino J, Carpi M, Conte A, Cruzat J, D’Antonio F, Della Penna S, Del Percio C, De Sanctis P, Escudero J, Fabbrini G, Farina FR, Fraga FJ, Fuhr P, Gschwandtner U, Güntekin B, Guo Y, Hajos M, Hallett M, Hampel H, Hanoğlu L, Haraldsen I, Hassan M, Hatlestad-Hall C, Horváth AA, Ibanez A, Infarinato F, Jaramillo-Jimenez A, Jeong J, Jiang Y, Kamiński M, Koch G, Kumar S, Leodori G, Li G, Lizio R, Lopez S, Ferri R, Maestú F, Marra C, Marzetti L, McGeown W, Miraglia F, Moguilner S, Moretti DV, Mushtaq F, Noce G, Nucci L, Ochoa J, Onorati P, Padovani A, Pappalettera C, Parra MA, Pardini M, Pascual-Marqui R, Paulus W, Pizzella V, Prado P, Rauchs G, Ritter P, Salvatore M, Santamaria-García H, Schirner M, Soricelli A, Taylor JP, Tankisi H, Tecchio F, Teipel S, Kodamullil AT, Triggiani AI, Valdes-Sosa M, Valdes-Sosa P, Vecchio F, Vossel K, Yao D, Yener G, Ziemann U, Kamondi A. Alpha Rhythm and Alzheimer’s Disease: Has Hans Berger’s Dream Come True? Clinical Neurophysiology 2025, 172:33-50. doi: 10.1016/j.clinph.2025.02.256. PMC In Process
- Chatterjee A, Lee S, Diaz V, Saloner R, Sanderson-Cimino M, DeCarli C, Maillard P, Hinman J, Vossel K, Casaletto KB, Staffaroni AM, Paolillo EW, Kramer JH. Effects of Cerebrovascular Disease and Alzheimer’s Disease Pathology on Cognitive Decline: Analysis of the National Alzheimer’s Coordinating Center Uniform Data Set. Neurobiology of Aging.
- Prabhu P, Morise H, Kudo K, Beagle A, Mizuiri D, Syed F, Kotegar KA, Findlay A, Miller BL, Kramer JH, Rankin KP, Garcia PA, Kirsch HE, Vossel K, Nagarajan SS, Ranasinghe KG, Abnormal Gamma Frequency Phase-Amplitude Coupling in the Parahippocampal Cortex is Associated with Network Hyperexcitability in Alzheimer’s Disease. Brain Commun. 2024 Apr 9;6:fcae121. doi: 10.1093/braincomms/fcae121. PMC11043655
- Kudo K, Ranasinghe KG, Morise H, Syed F, Sekihara K, Rankin KP, Miller BL, Kramer JH, Rabinovici GD, Vossel K, Kirsch HE, and Nagarajan SS. Neurophysiological trajectories in Alzheimer's disease progression. Elife 2024 Mar 28:12:RP91044. doi: 10.7554/eLife.91044. PMC10977971
- Verma P, Ranasinghe KG, Prasad J, Cai C, Xie X, Lerner H, Mizuiri D, Miller B, Rankin K, Vossel K, Cheung S, Nagarajan SS, Raj A. Impaired long-range excitatory time scale predicts abnormal neural oscillations and cognitive deficits in Alzheimer’s disease. Alzheimer's Research & Therapy 2024 Mar 19;16:62. doi: 10.1186/s13195-024-01426-7. PMC10953266
- Vicente M, Addo-Osafo K, and Vossel K. Latest Advances in Mechanisms of Epileptic Activity in Alzheimer’s Disease and Dementia with Lewy Bodies. Frontiers in Neurology 2024, Volume 15. doi: 10.3389/fneur.2024.1277613. PMC10882721
- Kern KC, Vohra M, Thirion ML, Wang DJJ, Wilcock DM, Thompson JF, Rosenberg GA, Sagare A, Moghekar A, Lu H, Lee T, Elahi FM, Barrera CS, Tracy R, Seshadri S, Schwab K, Helmer K, Singh H, Kivisäkk P, Greenberg S, Vossel K, Kramer JH, Maillard P, DeCarli CS, Hinman JD. White matter free water mediates the associations between placental growth factor, white matter hyperintensities, and cognitive status. Alzheimer’s & Dementia 2024. doi: 10.1002/alz.14408.
- Fu M, Valiente-Banuet L, Wadhwa SS, UCLA Precision Health Data Discovery Repository Working Group, UCLA Precision Health ATLAS Working Group, Pasaniuc B, Vossel K, Chang TS. Improving genetic risk modeling of dementia from real-world data in underrepresented populations. Communications Biology 2024 7:1049. doi: 10.1038/s42003-024-06742-0. PMC11345412
- Leeman-Markowski B, Chin J, Leitnerd D, Vossel K. Editorial: Epilepsy and Alzheimer’s disease: shared pathology, clinical presentations, and targets for treatment. Frontiers in Neurology 2024, 15:1441996. doi: 10.3389/fneur.2024.1441996. PMC11348586
- Vossel K. Putting the Brakes on Accelerated Cognitive Decline in Alzheimer’s Disease with Epileptic Activity. Journal of Alzheimer’s Disease 2023, 94:1075-1077. doi: 10.3233/JAD-230613. PMC10473065
- Hickman LB, Stern JM, Silverman DH, Salamon N, Vossel K. Clinical, imaging, and biomarker evidence of amyloid- and tau-related neurodegeneration in late-onset epilepsy of unknown etiology. Frontiers in Neurology 2023 Sep 27;14:1241638. doi: 10.3389/fneur.2023.1241638. PMC10565489
- Fan JM, Kudo K, Verma P, Ranasinghe KG, Morise H, Findlay AM, Vossel K, Kirsch HE, Raj A, Krystal AD, Nagarajan SS. Cortical synchrony and information flow during transition from wakefulness to light non-rapid eye movement sleep. The Journal of Neuroscience 2023 Oct 3:JN-RM-0197-23. doi: 10.1523/JNEUROSCI.0197-23.2023. PMC10697405
- Jin H, Ranasinghe K G, Prabhu P, Dale C, Gao Y, Kudo K, Vossel K, Raj A, Nagarajan SS, Jiang F. Dynamic functional connectivity MEG features of Alzheimer’s disease. Neuroimage 2023 Nov 1;281:120358. doi: 10.1016/j.neuroimage.2023.120358. PMC1086599
- Kim KX, Dale CL, Ranasinghe KG, Kothare H, Beagle AJ, Lerner H, Mizuiri D, Gorno-Tempini ML, Vossel K, Nagarajan SS, Houde JF. Impaired Speaking-Induced Suppression in Alzheimer's Disease. eNeuro 2023. doi: 10.1523/ENEURO.0056-23.2023. PMC10249944
- Falgàs N, Walsh CW, Yack L, Simon AJ, Kramer JH, Rosen H, Rabinovici G, Miller B, Spina S, Seeley WW, Ranasinghe K, Vossel K, Neylan TC, Grinberg LT. Alzheimer's disease phenotypes show different sleep architecture. Alzheimer’s and Dementia 2023 Aug 19.
- Hwang K, Vaknalli R, Addo-Osafo K, Vicente M, Vossel K. Tauopathy and Epilepsy Comorbidities and Underlying Mechanisms. Frontiers in Aging Neuroscience 2022. PMCID: PMC9340804
- Ranasinghe KG, Verma P, Cai C, Xie X, Kudo K, Gao X, Lerner H, Mizuiri D, Strom A, Iaccarino L, La Joie R, Miller BL, Gorno-Tempini ML, Rankin KP, Jagust WJ, Vossel K, Rabinovici GD, Raj A, Nagarajan SS. Altered excitatory and inhibitory neuronal subpopulation parameters are distinctly associated with tau and amyloid in Alzheimer’s disease. eLife 2022. PMCID: PMC9217132
- Oh JY, Walsh CM, Ranasinghe K, Mladinov M, Pereira FL, Petersen C, Falgàs N, Ruoff L, Lamore T, Nasar R, Lew C, Li S, Metzler T, Coppola Q, Pandher N, Le M, Heuer HW, Heinsen H, Spina S, Seeley WW, Kramer J, Rabinovici GD, Boxer AL, Miller BL, Vossel K, Neylan TC, Grinberg LT. Subcortical Neuronal Correlates of Sleep in Neurodegenerative Diseases. JAMA Neurology 2022 Apr 4;e220429. PMCID: PMC8981071
- Ranasinghe KG, Kudo K, Hinkley L, Beagle AJ, Lerner H, Mizuiri D, Findlay A, Miller BL, Kramer JH, Gorno-Tempini ML, Rabinovici GD, Rankin KP, Garcia PA, Kirsch HE, Vossel K (co-senior author), Nagarajan SS (co-senior author). Neuronal synchrony abnormalities associated with subclinical epileptiform activity in early-onset Alzheimer’s disease. Brain 2021 Dec 17;awab442. PMC9630715
- Vossel K, Ranasinghe KG, Beagle AJ, et al. Effect of Levetiracetam on Cognition in Patients With Alzheimer Disease With and Without Epileptiform Activity: A Randomized Clinical Trial. JAMA Neurology 2021. PMC8477304
- Vossel K, Karageorgiou E. Editorial: Silent Seizures and Memory Loss in Alzheimer's Disease. Frontiers in Neurology 2021;12:648650. PMCID: PMC7982410
- Ranasinghe KG, Petersen C, Kudo K, Mizuiri D, Rankin KP, Rabinovici GD, Seeley WW, Spina S, Miller BL, Vossel K, Grinberg LT, Nagarajan SS. Reduced synchrony in alpha oscillations during life predicts postmortem neurofibrillary tangle density in early-onset and atypical Alzheimer's disease. Alzheimer's & Dementia 2021. PMCID: PMC8528895
- Shields L, Li H, Nguyen K, Kim H, Doric Z, Gill TM, Haddad D, Vossel K, Calvert M, Nakamura K. Mitochondrial fission is a critical modulator of mutant APP-induced neural toxicity. Journal of Biological Chemistry 2021, 296:100469. PMCID: PMC8042169
- Castro M, Venkateswaran N, Peters S, K, Deyle DR, Bower M, Boeve BF, Vossel K. Case Report: Early-Onset Behavioral Variant Frontotemporal Dementia in Patient With Retrotransposed Full-Length Transcript of Matrin-3 Variant 5. Frontiers in Neurology, 2020.
- Johnson, EL, Krauss GL, Kucharska-Newton A, Albert MS, Brandt J, Walker KA, Yasar S, Knopman DS, Vossel K, Gottesman RF. Dementia in late-onset epilepsy: the Atherosclerosis Risk in Communities study. Neurology 2020, 95:e3248-e3256. PMCID: PMC7836657
- Peters ST, Fahrenkopf A, Choquette JM, Vermilyea S, Lee MK, Vossel K. Ablating Tau Reduces Hyperexcitability and Moderates Electroencephalographic Slowing in Transgenic Mice Expressing A53T Human α-Synuclein. Frontiers in Neurology 2020, 11:563. PMCID: PMC7316964
- Borghesani V, Hinkley LB, Ranasinghe KG, Thompson MMC, Shwe W, Mizuiri D, Lauricella M, Europa E, Honma S, Miller Z, Miller B, Vossel K, Houde JF, Gorno-Tempini ML, Nagarajan SS. Taking the sublexical route: brain dynamics of reading in the semantic variant of primary progressive aphasia. Brain 2020 143:2545-2560. PMCID: PMC7447517
- Ranasinghe KG, Cha J, Hinkley LB, Beagle AJ, Jagust W, Miller BL, Rankin KP, Rabinovici GD, Vossel KA (co-senior author), Nagarajan SS (co-senior author). Neurophysiological signatures in Alzheimer’s disease are distinctly associated with TAU, amyloid-β accumulation, and cognitive decline. Science Translational Medicine 2020. PMCID: PMC7138514
- Gamache J, Kemper L, Steuer E, Leinonen K, Choquette J, Hlynialuk C, Benzow K, Vossel KA, Xia W, Koob M, Ashe KH. Developmental Pathogenicity of 4-Repeat Human Tau Is Lost with the P301L Mutation in Genetically Matched Tau-Transgenic Mice. Journal of Neuroscience 2019, 40:220-236. PMCID: PMC6939485
- Ranasinghe KG, Kothare H, Kort N, Hinkley LB, Beagle AJ, Mizuiri D, Honma SM, Lee R, Miller BL, Gorno-Tempini ML, Vossel KA, Houde JF, Nagarajan SS. Neural correlates of abnormal auditory feedback processing during speech production in Alzheimer’s disease. Scientific Reports 2019, 9:5686. PMCID: PMC6450891
- La AL, Walsh CM, Neylan TC, Vossel KA, Yaffe K, Krystal AD, Miller BL, Karageorgiou E. Long-Term Trazodone Use and Cognition: A Potential Therapeutic Role for Slow-Wave Sleep Enhancers. Journal of Alzheimer’s Disease 2019, 67:911-921. PMCID: PMC6398835
- Lutsey PL, Chen N, Lakshminarayan K, Gottesman RF, Mosley TH, Knopman DS, Vossel KA, Mirabelli MC, Alonso A. Impaired Lung Function, Lung Disease, and Risk of Incident Dementia. American Journal of Respiratory and Critical Care Medicine 2019, 199(11):1385-1396. PMCID: PMC6543713
- Vossel KA, Tartaglia MC, Nygaard HB, Zeman AZ, Miller BL. Epileptic activity in Alzheimer's disease: causes and clinical relevance. The Lancet Neurology 2017, 16:311-322. PMCID: PMC5973551
- Beagle AJ, Darwish SM, Ranasinghe KG, La AL, Karageorgiou E, Vossel KA. Relative Incidence of Seizures and Myoclonus in Alzheimer’s Disease, Dementia with Lewy Bodies, and Frontotemporal Dementia. Journal of Alzheimer’s Disease 2017, 60:211-223. PMCID: PMC5608587
- Karageorgiou E and Vossel KA. Brain rhythm attractor breakdown in Alzheimer's disease: Functional and pathologic implications. Alzheimer's & Dementia 2017, 13:1054-1067. PMCID: PMC5585024
- Perry DC, Brown J, Possin KL, Datta S, Trujillo A, Radke A, Karydas A, Kornak J, Sias AC, Rabinovici GD, Gorno-Tempini ML, Boxer AL, De May M, Rankin KP, Sturm VE, Lee S, Matthews BR, Kao AW, Vossel KA, Tartaglia MC, Miller ZA, Seo SW, Sidhu M, Gaus SE, Li AN, Vargas JN, Hwang J, Ossenkoppele R, Brown AB, Huang EJ, DeArmond SJ, Coppola G, Rosen HJ, Geschwind D, Trojanowski JQ, Grinberg LT, Kramer JH, Miller BL, Seeley WW. Clinicopathological correlations in behavioural variant frontotemporal dementia. Brain 2017, 140:3329-3345. PMCID: PMC5841140
- Ranasinghe KG, Hinkley LB, Beagle AJ, Mizuiri D, Honma SM, Welch AE, Hubbard I, Mandelli ML, Miller ZA, Garrett C, La A, Boxer AL, Houde JF, Miller BL, Vossel KA, Gorno-Tempini ML, Nagarajan SS. Distinct spatiotemporal patterns of neuronal functional connectivity in primary progressive aphasia variants. Brain 2017, 140:2737- 2751. PMCID: PMC5841154
- Miyamoto T, Stein L, Taneja P, Djukic B, Knox J, Vossel K, Mucke L. Phosphorylation of tau at Y18, but not tau-fyn binding, is required for tau to modulate NMDA receptor-dependent excitotoxicity in primary neuronal culture. Molecular Neurodegeneration 2017, 12:41. PMCID: PMC5438564
- Ranasinghe KG, Gill JS, Kothare H, Beagle AJ, Mizuiri D, Honma SM, Gorno-Tempini ML, Miller BL, Vossel KA, Houde JF, Nagarajan SS. Abnormal vocal behavior predicts executive and memory deficits in Alzheimer's disease. Neurobiology of Aging 2017, 52:71-80. PMCID: PMC5359035
- Vossel KA, Ranasinghe KG, Beagle AJ, Mizuiri D, Honma SM, Dowling AF, Darwish SM, Barnes DE, Mantle M, Roberson ED, Miller BL, Garcia PA, Kirsch HE, Mucke L, Nagarajan SS. Incidence and impact of subclinical epileptiform activity in Alzheimer's disease. Annals of Neurology 2016, 80:858-870. PMCID: PMC5177487
- Ranasinghe KG, Rankin KP, Pressman PS, Perry DC, Lobach IV, Seeley WW, Coppola G, Karydas AM, Grinberg LT, Shany-Ur T, Lee SE, Rabinovici GD, Rosen HJ, Gorno-Tempini ML, Boxer AL, Miller ZA, Chiong W, DeMay M, Kramer JH, Possin KL, Sturm VE, Bettcher BM, Neylan M, Zackey DD, Nguyen LA, Ketelle R, Block N, Wu TQ, Dallich A, Russek N, Caplan A, Geschwind DH, Vossel KA, Miller BL. Distinct Subtypes of Behavioral Variant Frontotemporal Dementia Based on Patterns of Network Degeneration. JAMA Neurology 2016, 73:1078-1088. PMCID: PMC5024785
- Ossenkoppele R, Schonhaut DR, Schöll M, Lockhart SN, Ayakta N, Lazaris A, Cantwell A, Vogel J, Baker SL, O’Neil JP, Janabi M, Santos M, Miller ZA, Bettcher BM, Vossel KA, Kramer JH, Gorno-Tempini ML, Miller BL, Jagust WJ, Rabinovici GD. Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer’s disease. Brain 2016, 139:1551-1567. PMCID: PMC5006248
- Ranasinghe KG, Rankin KP, Lobach IV, Kramer JH, Sturm VE, Bettcher BM, Possin K, You SC, Lamarre AK, Shany-Ur T, Stephens ML, Perry DC, Lee SE, Miller ZA, Gorno-Tempini ML, Rosen HJ, Boxer A, Seeley WW, Rabinovici GD, Vossel KA, Miller BL. Cognition and neuropsychiatry in behavioral variant frontotemporal dementia by disease stage. Neurology 2016, 86:600-610. PMCID: PMC4762418
- Morris M, Sanchez PE, Verret L, Beagle AJ, Guo W, Dubal D, Ranasinghe KG, Koyama A, Vossel KA, Mucke L. Network dysfunction in α-synuclein transgenic mice and human Lewy body dementia. Annals of Clinical and Translational Neurology 2015, 2:1012-1028. PMCID: PMC4693622
- Vossel KA, Xu JC, Fomenko V, Miyamoto T, Suberbielle E, Knox JA, Ho K, Yu G, Mucke L. Tau reduction prevents Aβ-induced axonal transport deficits by blocking activation of GSK3β. The Journal of Cell Biology 2015, 209:419-433. PMCID: PMC4427789
- Ranasinghe KG, Hinkley LB, Beagle AJ, Mizuiri D, Dowling AF, Honma SM, Finucane MM, Scherling C, Miller BL, Nagarajan SS, Vossel KA. Regional functional connectivity predicts distinct cognitive impairments in Alzheimer’s disease spectrum. NeuroImage Clinical 2014, 5:385–395. PMCID: PMC4145532
- Vossel KA, Beagle AJ, Rabinovici GD, Shu H, Lee SE, Naasan G, Hegde M, Cornes SB, Henry ML, Nelson AB, Seeley WW, Geschwind MD, Gorno-Tempini ML, Shih T, Kirsch HE, Garcia PA, Miller BL, Mucke L. Seizures and Epileptiform Activity in the Early Stages of Alzheimer Disease. JAMA Neurology 2013, 70:1158-66. PMCID: PMC4013391
- Vossel KA, Bien-Ly N, Bernardo A, Rascovsky K, Karydas A, Rabinovici GD, Sidhu M, Huang EJ, Miller BL, Huang Y, Seeley WW. ApoE and TDP-43 neuropathology in two siblings with familial FTLD-motor neuron disease. Neurocase 2013, 19:295- 301. PMCID: PMC3655113
- Sanchez PE, Zhu L, Verret L, Vossel KA, Orr AG, Cirrito JR, Devidze N, Yu G, Palop JJ, Mucke L. Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer’s disease model. Proceedings of the National Academy of Sciences U.S.A. 2012, 109:E2895-2903. PMCID: PMC3479491
